Julio César Hechavarria Cueria
I am currently leading the Neurobiology of Auditory Computations (NAC) group. The NAC group is a part of the Department for Neurobiology and Biosensors, located at the Goethe University of Frankfurt am Main. In the NAC group, we use bats, gerbils and humans as models for understanding the rules that govern vocal production in mammals. A large part of our research also deals with the mechanisms by which the brain is able to extract and piece together the information enclosed in natural sound streams.
We always have several research projects running in parallel. These projects are conducted by PhD, master, and bachelor students under my supervision, and the supervision of Prof. Manfred Kössl. Currently ongoing research projects include:
External funding sources
DFG: grant number HE 7478/1-1
Open PhD positions
Currently there are no open PhD positions in the NAC lab, but we are always searching for highly motivated PhD candidates. Feel free to contact us if you are interested in investigating auditory processing in the bat brain.
Topics for Master and Bachelor thesis
We are always searching for master and bachelor students that are highly motivated to study auditory processing. Feel free to contact us to know more about possible topics for bachelor and master thesis.
* = recommended readings
Publications 2018 - top
Hechavarría J, Kössl M (2018) Smart bats click twice. DOI: https://doi.org/10.7554/eLife.36561
Beetz M J, García-Rosales F, Kössl M, Hechavarría J C, (2018) Robustness of cortical and subcortcal processing in the presence of natural masking sounds DOI:10.1038/s41598-018-25241-x
García-Rosales F, Martin L M, Beetz M J, Cabral-Calderin Y, Kössl M, Hechavarría J C, (2018) Low-Frequency Spike-Field Coherence Is a Fingerprintof Periodicity Coding in the Auditory Cortex. https://oi.org/10.1016/j.isci.2018.10.009
Publications 2017 - top
Schaefer M K, Kössl M, Hechavarria J Cm (2017) Laminar differences in response to simple and spectro-temporally complex sounds in the primary auditory cortex of ketmine-anesthetized gerbils. PLOS ONE https://doi.org/10.1371/journal.pone.0182514
Kössl M, Hchavarría J C (2017) Die Zeitkarte im Gehirn - Wie Feldermäuse Raum in Zeit übersetzen. Forschung Frankfurt 1.2017
Beetz M J, Kordes S, García-Rosales F, Kössl M, Hechavarría J C, (2017) Processing of Natural Echolocation Sequences in the Inferior Colliculus of Seba's Fruit Eating Bat, Carollia perspicillata DOI:http://dx.doi.org/10.15.23/ENEURO.0314-17.2017
Martin L M, García-Rosales F, Beetz M J, Hechavarría J C, (2017) Processing of temporally patterned sounds in the auditory cortex of Seba's short-tailed bat, Carollia perspicillata DOI:10.1111/ejn.13702
Publications 2016 - top
*Vocal sequences suppress spiking in the bat auditory cortex while evoking concomitant steady-state local field potentials. Hechavarría JC, Beetz MJ, Macias S, Kössl M. Sci Rep. 2016 Dec 15;6:39226. doi: 10.1038/srep39226
Cortical neurons of bats respond best to echoes from nearest targets when listening to natural biosonar multi-echo streams. Beetz MJ, Hechavarría JC, Kössl M. Sci Rep. 2016 Oct 27;6:35991. doi: 10.1038/srep35991.
Short delays and low pulse amplitudes produce widespread activation in the target-distance processing area of auditory cortex of the mustached bat. Macías S, Hechavarría JC. J Acoust Soc Am. 2016 Aug;140(2):917. doi: 10.1121/1.4960547.
Sharp temporal tuning in the bat auditory midbrain overcomes spectral-temporal trade-off imposed by cochlear mechanics. Macías S, Hechavarría JC, Kössl M. Sci Rep. 2016 Jul 4;6:29129. doi: 10.1038/srep29129.
*Temporal tuning in the bat auditory cortex is sharper when studied with natural echolocation sequences. Beetz MJ, Hechavarría JC, Kössl M. Sci Rep. 2016 Jun 30;6:29102. doi: 10.1038/srep29102.
The electrocardiogram signal of Seba's short-tailed bat, Carollia perspicillata. Mihova D, Hechavarría JC. J Comp Physiol A. 2016 Jul;202(7):517-26. doi: 10.1007/s00359-016-1098-8. PMID: 27283857
*Distress vocalization sequences broadcasted by bats carry redundant information. Hechavarría JC, Beetz MJ, Macias S, Kössl M. J Comp Physiol A. 2016 Jul;202(7):503-15. doi: 10.1007/s00359-016-1099-7. PMID: 27277892
Echo-level compensation and delay tuning in the auditory cortex of the mustached bat. Macías S, Mora EC, Hechavarría JC, Kössl M. Eur J Neurosci. 2016 Jun;43(12):1647-60. doi: 10.1111/ejn.13244. PMID: 27037932
*Temporal encoding precision of bat auditory neurons tuned to target distance deteriorates on the way to the cortex. Macías S, Hechavarría JC, Kössl M. J Comp Physiol A. 2016 Mar;202(3):195-202. doi: 10.1007/s00359-016-1067-2.
Beetz MJ, Hechavarría JC, Kössl M (2016) Precise target-distance coding during cortical suppression in echolocating bats.
Publications 2015 - top
Kössl M, Hechavarria J, Voss C, Schaefer M, Vater M (2015) Bat auditory cortex - model for general mammalian auditory computation or special design solution for active time perception? European Journal of Neuroscience 41(5):518-32. doi: 10.1111/ejn.12801.
Macías S, Hernández-Abad A, Hechavarría JC, Kössl M, Mora EC (2015) Level-tolerant duration selectivity in the auditory cortex of the velvety free-tailed bat Molossus molossus. Journal of Comparative Physiology A (2015)201:461-471. doi 10.1007/s00359-015-0993-8
Schaefer M, Hechavarria JC, Koessl M (2015) Quantification of mid and late evoked sinks in laminar current source density profiles of columns in the primary auditory cortex. frontiers in Neural Circuits. doi: 10.3389/fncir.2015.00052
Beetz MJ, Hechavarría JC, Kössl M (2015). About how cortical neurons of bats cope with fast echolocation sequences: Multi-electrode and single-electrode recordings with natural echolocation stimuli. “Eleventh Göttingen Meeting of the German Neuroscience Society” (Göttingen, Germany, 18.-21. March 2015).
Publications 2014 - top
Hechavarria JC, Kössl M (2014) Footprints of inhibition in the response of cortical delay-tuned neurons of bats. Journal of Neurophysiology 111:1703-1716.
Kössl M, Hechavarria JC, Voss C, Macias S, Mora EC, Vater M (2014) Neural maps for target range in the auditory cortex of echolocating bats. Current Opinion in Neurobiology 24:68-75.
Macias S, Hechavarria JC, Cobo A, Mora EC (2014) Narrow sound pressure level tuning in the auditory cortex of the bats Molossus molossus and Macrotus waterhousii. Hearing Research 309:36-43.
Mora EC, Fernández Y, Hechavarría J, Pérez M (2014) Tone-deaf ears in moths may limit the acoustic detection of two-tone bats. Brain Behavior and Evolution 83(4): 275-85.