Find all our publications here.

Selected relevant publications from previous work:

Tants JN, Schlundt A. Advances, Applications, and Perspectives in Small-Angle X-Ray Scattering of RNA.

ChemBioChem. 2023 (in press). Coverstory!

Available at: https://doi.org/10.1002/cbic.202300110

Korn SM, Dhamotharan K, Jeffries CM, Schlundt A. The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.

Nat. Commun. 2023 Jun 7.

Available at: https://doi.org/10.1038/s41467-023-38882-y

von Ehr J, Korn SM, Weiß L, Schlundt A. 1H, 13C, 15N backbone chemical shift assignments of the extended ARID domain in human AT-rich interactive domain protein 5a (Arid5a).

Biomol. NMR Assign. 2023 Jun;17.

Available at: https://doi.org/10.1007/s12104-023-10130-w

Schulte J, Tants JN, Von Ehr J, Schlundt A, Morgner N. Determination of dissociation constants via quantitative mass spectrometry.

Front Anal. Sci. 2023 Feb 24.

Available at: https://doi.org/10.3389/frans.2023.1119489

Korn SM, Von Ehr J, Dhamotharan K, Tants JN, Abele R, Schlundt A. Insight into the Structural Basis for Dual Nucleic Acid-Recognition by the Scaffold Attachment Factor B2 Protein.

Int J Mol Sci. 2023 Feb 7.

Available at: https://doi.org/10.3390/ijms24043286

Duchardt-Ferner E, Ferner J, Fürtig B, Hengesbach M, Richter C, Schlundt A, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Schwalbe H. The COVID19-NMR Consortium: A Public Report on the Impact of this New Global Collaboration.

Angew Chem Int Ed Engl. Epub 2023 Feb 7.

Available at: https://doi.org/10.1002/anie.202217171

Berg H, Wirtz Martin MA, Altincekic N, Alshamleh I, Kaur Bains J, Blechar J, Ceylan B, de Jesus V, Dhamotharan K, Fuks C, Gande SL, Hargittay B, Hohmann KF, Hutchison MT, Marianne Korn S, Krishnathas R, Kutz F, Linhard V, Matzel T, Meiser N, Niesteruk A, Pyper DJ, Schulte L, Trucks S, Azzaoui K, Blommers MJJ, Gadiya Y, Karki R, Zaliani A, Gribbon P, da Silva Almeida M, Dinis Anobom C, Bula AL, Bütikofer M, Putinhon Caruso Í, Caterina Felli I, Da Poian AT, Cardoso de Amorim G, Fourkiotis NK, Gallo A, Ghosh D, Gomes-Neto F, Gorbatyuk O, Hao B, Kurauskas V, Lecoq L, Li Y, Cunha Mebus-Antunes N, Mompeán M, Cristtina Neves-Martins T, Ninot-Pedrosa M, Pinheiro AS, Pontoriero L, Pustovalova Y, Riek R, Robertson AJ, Jose Abi Saad M, Treviño MÁ, Tsika AC, Almeida FCL, Bax A, Henzler-Wildman K, Hoch JC, Jaudzems K, Laurents DV, Orts J, Pierattelli R, Spyroulias GA, Duchardt-Ferner E, Ferner J, Fürtig B, Hengesbach M, Löhr F, Qureshi N, Richter C, Saxena K, Schlundt A, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J, Schwalbe H. Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development.

Angew Chem Int Ed Engl. 2022 Nov 14.

Available at: https://doi.org/10.1002/anie.202205858

Pontoriero L, Schiavina M, Korn SM, Schlundt A*, Pierattelli R*, Felli IC*. NMR Reveals Specific Tracts within the Intrinsically Disordered Regions of the SARS-CoV-2 Nucleocapsid Protein Involved in RNA Encountering.

Biomolecules. 2022 Jul 2.

Available at: https://doi.org/10.3390/biom12070929

Mertinkus KR, Grün JT, Altincekic N, Bains JK, Ceylan B, Ferner JP, Frydman L, Fürtig B, Hengesbach M, Hohmann KF, Hymon D, Kim J, Knezic B, Novakovic M, Oxenfarth A, Peter SA, Qureshi NS, Richter C, Scherf T, Schlundt A, Schnieders R, Schwalbe H, Stirnal E, Sudakov A, Vögele J, Wacker A, Weigand JE, Wirmer-Bartoschek J, Martin MAW, Wöhnert J. 1H, 13C and 15N chemical shift assignment of the stem-loops 5b + c from the 5'-UTR of SARS-CoV-2.

Biomol. NMR Assign. 2022 Apr 16.

Available at: https://doi.org/10.1007/s12104-021-10053-4

Tants JN, Becker LM, McNicoll F, Müller-McNicoll M, Schlundt A. NMR-derived secondary structure of the full-length Ox40 mRNA 3'UTR and its multivalent binding to the immunoregulatory RBP Roquin.

Nucleic Acids Res. 2022 Apr 22.

Available at: https://doi.org/10.1093/nar/gkac212

Korn SM, Schlundt A. Structures and nucleic acid-binding preferences of the eukaryotic ARID domain. Review.

Biol Chem. 2022 Feb 7.

Available at: https://doi.org/10.1515/hsz-2021-0404

Schamber T, Binas O, Schlundt A, Wacker A, Schwalbe H. Characterization of Structure and Dynamics of the Guanidine-II Riboswitch from Escherichia coli by NMR Spectroscopy and Small-Angle X-ray Scattering (SAXS).

Chembiochem. 2022 Feb 4

Available at: https://doi.org/10.1002/cbic.202100564

Sreeramulu S, Richter C, Berg H, Wirtz Martin MA, Ceylan B, Matzel T, Adam J, Altincekic N, Azzaoui K, Bains JK, Blommers MJJ, Ferner J, Fürtig B, Göbel M, Grün JT, Hengesbach M, Hohmann KF, Hymon D, Knezic B, Martins JN, Mertinkus KR, Niesteruk A, Peter SA, Pyper DJ, Qureshi NS, Scheffer U, Schlundt A, Schnieders R, Stirnal E, Sudakov A, Tröster A, Vögele J, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J, Schwalbe H. Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS-CoV-2 Genome.

Angew Chem Int Ed Engl. 2021Aug 23 (online).

Available at: https://doi.org/10.1002/anie.202103693

Korn SM, Ulshöfer C, Schneider T, Schlundt A. Structures and target RNA preferences of the multi-domain RNA-binding protein family of IGF2BPs: An overview. Review.

Structure. 2021May 21 (online).

Available at: https://doi.org/10.1016/j.str.2021.05.001

Altincekic N, Korn SM, Qureshi NS, Dujardin M, Ninot-Pedrosa M, …, Böckmann A*, …, Schwalbe H*, …,  Hengesbach M*, Schlundt A*. Large-scale recombinant production of the SARS-CoV-2 proteome for high-throughput and structural biology applications.

Front Mol. Biosci. 2021 May 10 (online).

Available at: https://doi.org/10.3389/fmolb.2021.653148

Wang Y, Kirkpatrick J, Zur Lage S, Korn SM, Neißner K, Schwalbe H, Schlundt A, Carlomagno T. 1H, 13C, and 15N backbone chemical-shift assignments of SARS-CoV-2 non-structural protein 1 (leader protein).

Biomol NMR Assign. 2021 Mar 26:1-9.

Available at: https://doi.org/10.1007/s12104-021-10019-6

F Dudás E, Puglisi R, Korn SM, Alfano C, Bellone ML, Piaz FD, Kelly G, Monaca E, Schlundt A, Schwalbe H, Pastore A. Backbone chemical shift spectral assignments of SARS coronavirus-2 non-structural protein nsp9.

Biomol NMR Assign. 2021 Mar 23:1-7.

Available at: https://doi.org/10.1007/s12104-021-10011-0

Korn SM, Lambertz R, Fürtig B, Hengesbach M, Löhr F, Richter C, Schwalbe H, Weigand JE, Wöhnert J, Schlundt A. 1H, 13C, and 15N backbone chemical shift assignments of the C-terminal dimerization domain of SARS-CoV-2 nucleocapsid protein.

Biomol NMR Assign. 2021 Apr;15(1):129-135.

Available at: https://doi.org/10.1007/s12104-020-09995-y

Korn SM, Dhamotharan K, Fürtig B, Hengesbach M, Löhr F, Qureshi NS, Richter C, Saxena K, Schwalbe H, Tants JN, Weigand JE, Wöhnert J, Schlundt A. 1H, 13C, and 15N backbone chemical shift assignments of the nucleic acid-binding domain of SARS-CoV-2 non-structural protein 3e.

Biomol NMR Assign. 2020 Oct;14(2):329-333.

Available at: https://doi.org/10.1007/s12104-020-09971-6

Wacker A, Weigand JE, Akabayov SR, Altincekic N, Bains JK, Banijamali E, Binas O, Castillo-Martinez J, Cetiner E, Ceylan B, Chiu LY, Davila-Calderon J, Dhamotharan K, Duchardt-Ferner E, Ferner J, Frydman L, Fürtig B, Gallego J, Grün JT, Hacker C, Haddad C, Hähnke M, Hengesbach M, Hiller F, Hohmann KF, Hymon D, de Jesus V, Jonker H, Keller H, Knezic B, Landgraf T, Löhr F, Luo L, Mertinkus KR, Muhs C, Novakovic M, Oxenfarth A, Palomino-Schätzlein M, Petzold K, Peter SA, Pyper DJ, Qureshi NS, Riad M, Richter C, Saxena K, Schamber T, Scherf T, Schlagnitweit J, Schlundt A, Schnieders R, Schwalbe H, Simba-Lahuasi A, Sreeramulu S, Stirnal E, Sudakov A, Tants JN, Tolbert BS, Vögele J, Weiß L, Wirmer-Bartoschek J, Wirtz Martin MA, Wöhnert J, Zetzsche H. Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy.

Nucl. Acid. Res. 2020 Dec 16;48(22):12415-12435.

Available at: https://doi.org/10.1093/nar/gkaa1013

Binas O, Tants JN, Peter S, Janowski R, Davydova E, Braun J, Niessing D,Schwalbe H, Weigand J*, Schlundt A*. Structural basis for the recognition of transiently structured AU-rich elements by Roquin.

Nucl. Acid. Res. 2020 Jul 27;48(13):7385-7403

Available at: https://doi.org/10.1093/nar/gkaa465

LingarajuM, Johnsen D, Schlundt A, Langer LM, Basquin J, Sattler M, Heick Jensen T, Falk S, Conti E. The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs.

Nat. Commun. 2019 Jul 29;10(1):3393.

Available at: https://doi.org/10.1038/s41467-019-11339-x

Schneider T, Hung LH, Aziz M, Wilmen A, Thaum S, Wagner J, Janowski R, Müller S, Hüttelmaier S, Niessing D, Sattler M, Schlundt A*, BindereifA*. Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3.

Nat. Commun. 2019 May 22;10(1):2266.

Available at: https://doi.org/ 10.1038/s41467-019-09769-8

Essig K, Kronbeck N, Guimaraes JC, Lohs C, Schlundt A, Hoffmann A, Behrens G, Brenner S, Kowalska J, Lopez-Rodriguez C, Jemielity J, Holtmann H, Reiche K, Hackermüller J, Sattler M, Zavolan M, Heissmeyer V. Roquin targets mRNAs in a 3′-UTR-specific manner by different modes of regulation.

Nat. Commun. 2018 Sep 19;9(1):3810.

Available at: https://doi.org/10.1038/s41467-018-06184-3

Schlundt A, Buchner S, Janowski R, Heydenreich T, Heermann R, Lassak J, Geerlof A, Stehle R, Niessing D, Jung K, Sattler M. Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator.

Sci. Rep. 2017 Apr 21; 1051.

Available at: https://doi.org/10.1038/s41598-017-01031-9

Schlundt A, Tants J, Sattler M. Integrated structural biology to unravel mechanisms of RNA-protein recognition. Review

Methods. 2017 Mar 16. pii: S1046-2023(17)30120-2.

Available at: https://doi.org/10.1016/j.ymeth.2017.03.015.

Edelmann FT, Schlundt A, Heym RG, Jenner A, Niedner A, Syed MI, Paillart J, Stehle R, Janowski R, Sattler M, Jansen R, Niessing D. Molecular architecture and dynamics of RNA recognition by an mRNA-transport complex.

Nat. Struct. Mol. Biol. 2017 Feb;24(2):152-161.

Available at: https://doi.org/10.1038/nsmb.3351

Schlundt A*, Niessing D, Heissmeyer V, Sattler M*. RNA recognition by Roquin in posttranscriptional gene regulation. Review.

Wiley Interdiscipl. Rev. RNA. 2016 Jul;7(4):455-69.

Available at: https://doi.org/10.1002/wrna.1333

Janowski R*, Heinz GA*, Schlundt A*, Wommelsdorf N, Brenner S, Gruber AR, Blank M, Buch T, Buhmann R, Zavolan M, Niessing D, Heissmeyer V, Sattler M. Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.

Nat. Commun. 2016 Mar 24;7:11032.

Available at: https://doi.org/10.1038/ncomms11032

Buchner S, Schlundt A, Lassak J, Sattler M, Jung K. Structural and Functional Analysis of the Signal-Transducing Linker in the pH-Responsive One-Component System CadC of Escherichia coli.

J. Mol. Biol. 2015 Jul 31;427(15):2548-61.

Available at: https://doi.org/10.1016/j.jmb.2015.05.001

SchlundtA*, Heinz GA*, Janowski R*, Geerlof A, Stehle R, Heissmeyer V, Niessing D, Sattler M. Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.

Nat.Struct. Mol. Biol. 2014 Aug;21(8):671-8.

Available at: https://doi.org/10.1038/nsmb.2855

*equal contribution or corresponding authorship