Publications

2017|2016|2015|2014|2013|2012|2010|2008|2007|2006|2005|2004

2017


Nuclear retention of mRNAs - quality control, gene regulation and disease 
Wegener M, Müller-McNicoll M
 
Semin Cell Dev Biol. 2017 Nov 1. pii: S1084-9521(17)30442-1. doi: 10.1016/j.semcdb.2017.11.001

Fractionation iCLIP detects persistent SR protein binding to conserved, retained introns in chromatin, nucleoplasm and cytoplasm 
Brugiolo M, Botti V, Liu N, Müller-McNicoll M, Neugebauer KM
Nucleic Acids Research, PMID: 28977534 DOI: 10.1093/nar/gkx671

TGFβ/SMAD signalling modulates MLL and MLL-AF4 mediated 5-lipoxygenase promoter activation
Saul MJ, Groher F, Hegewald AB, Müller-McNicoll M, Marschalek R, Suess B, Steinhilber
Prostaglandins & Other Lipid Mediators, 2017, PMID: 28803964 doi: 10.1016/j.prostaglandins.2017.07.006

RNA secondary structure and nucleotide composition of the conserved hallmark sequence of Leishmania SIDER2 retroposons are essential for endonucleolytic cleavage and mRNA degradation
Hiva Azizi, Tatiany P. Romão, Karen Santos Charret, Prasad K. Padmanabhan, Osvaldo P. de Melo Neto, Michaela Müller-McNicoll, Barbara Papadopoulou
PLOS One, July 13, 2017, doi:https://doi.org/10.1371/journal.pone.0180678

Body Temperature Cycles Control Rhythmic Alternative Splicing in Mammals
Marco Preußner, Gesine Goldammer, Alexander Neumann,&nbspTom Haltenhof, Pia Rautenstrauch, Michaela Müller-McNicoll,Florian Heyd
Molecular Cell , Volume 67 , Issue 3 , 433 - 446.e4, doi: http://dx.doi.org/10.1016/j.molcel.2017.06.006

Cellular differentiation state modulates the mRNA export activity of SR proteins
Botti V, McNicoll F, Steiner MC, Richter FM, Solovyeva A, Wegener M, Schwich OD, Poser I, Zarnack K, Wittig I, Neugebauer KM, Müller-McNicoll M
J Cell Biol. 2017 Jun 7. pii: jcb.201610051. doi: 10.1083/jcb.201610051

SIDER2 retroposon-mediated mRNA decay in Leishmania is coupled to translation
Azizi H, Müller-McNicoll M, Papadopoulou B
J. MBio. 2017 Jan 31;8(1). pii: e02288-16. doi: 10.1128/mBio.02288-16.

Differential Binding of Mitochondrial Transcripts by MRB8170 and MRB4160 Regulates Distinct Editing Fates of Mitochondrial mRNA in Trypanosomes
Dixit S, Müller-McNicoll M, David V, Zarnack K, Ule J, Hashimi H, Lukeš
J. MBio. 2017 Jan 31;8(1). pii: e02288-16. doi: 10.1128/mBio.02288-16.

2016


SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export
Michaela Müller-McNicoll, Valentina Botti, Antonio M. de Jesus Domingues, Holger Brandl, Oliver D. Schwich, Michaela C. Steiner, Tomaz Curk, Ina Poser, Kathi Zarnack, and Karla M. Neugebauer
Genes & Dev. 2016. 30: 553-566, doi:10.1101/gad.276477.115

2015


Approaches for Studying mRNA Decay Mediated by SIDER2 Retroposons in Leishmania 
Barbara Papadopoulou, Michela Müller-McNicoll, Prasad K. Padmanabhan 
DOI: 10.1007/978-1-4939-1438-8_7 In book: Methods in Molecular Biology, Vol. 1201 Parasites Genomic Protocols, Chapter: Approaches for Studying mRNA Decay Mediated by SIDER2 Retroposons in Leishmania, Publisher: Springer, Editors: Christopher Peacock

2014


Good cap/bad cap: how the cap-binding complex determines RNA fate.
Müller-McNicoll M, Neugebauer KM
Nat Struct Mol Biol. 2014 Jan;21(1):9-12. doi: 10.1038/nsmb.2751.

2013


How cells get the message: dynamic assembly and function of mRNA-protein complexes.
Müller-McNicoll M, Neugebauer KM.
Nat Rev Genet. 2013 Apr;14(4):275-87. doi: 10.1038/nrg3434. Epub 2013 Mar 12.

2012


The RNA-binding landscapes of two SR proteins reveal unique functions and binding to diverse RNA classes.
Änkö ML, Müller-McNicoll M, Brandl H, Curk T, Gorup C, Henry I, Ule J, Neugebauer KM.
Genome Biol. 2012;13(3):R17. doi: 10.1186/gb-2012-13-3-r17.

2010


mRNA: a complex(ed) life.
Müller M, Neugebauer KM, Eckmann C.
Genome Biol. 2010;11(5):304. doi: 10.1186/gb-2010-11-5-304. Epub 2010 May 25.

Rapid decay of unstable Leishmania mRNAs bearing a conserved retroposon signature 3'-UTR motif is initiated by a site-specific endonucleolytic cleavage without prior deadenylation.
Müller M, Padmanabhan PK, Rochette A, Mukherjee D, Smith M, Dumas C, Papadopoulou B.
Nucleic Acids Res. 2010 Sep;38(17):5867-83. doi: 10.1093/nar/gkq349. Epub 2010 May 7.

Selective inactivation of SIDER2 retroposon-mediated mRNA decay contributes to stage- and species-specific gene expression in Leishmania.
Müller M, Padmanabhan PK, Papadopoulou B.
Mol Microbiol. 2010 Jul;77(2):471-91. doi: 10.1111/j.1365-2958.2010.07226.x. Epub 2010 May 24.

Stage-specific expression of the glycine cleavage complex subunits in Leishmania infantum.
Müller M, Papadopoulou B.
Mol Biochem Parasitol. 2010 Mar;170(1):17-27. doi: 10.1016/j.molbiopara.2009.11.009. Epub 2009 Dec 2.

2008


Identification of geographically distributed sub-populations of Leishmania (Leishmania) major by microsatellite analysis.
Al-Jawabreh A, Diezmann S, Müller M, Wirth T, Schnur LF, Strelkova MV, Kovalenko DA, Razakov SA, Schwenkenbecher J, Kuhls K, Schönian G.
BMC Evol Biol. 2008 Jun 24;8:183. doi: 10.1186/1471-2148-8-183.

Regulation of Gene Expression in Leishmania Throughout a Complex Digenetic Life Cycle 
Barbara Papadopoulou, Michaela Müller, Annie Rochette, Francois McNicoll,Carole Dumas, Conan Chow 
In book: Leishmania: After the Genome, Chapter: Regulation of Gene Expression in Leishmania Throughout a Complex Digenetic Life Cycle, Publisher: Horizon Scientific Press, Editors: Peter J Myler & Nicolas Fasel, pp.29-54 

2007


Members of a large retroposon family are determinants of post-transcriptional gene expression in Leishmania.
Bringaud F, Müller M, Cerqueira GC, Smith M, Rochette A, El-Sayed NM, Papadopoulou B, Ghedin E.
PLoS Pathog. 2007 Sep 7;3(9):1291-307.

2006


A novel class of developmentally regulated noncoding RNAs in Leishmania.
Dumas C, Chow C, Müller M, Papadopoulou B.
Eukaryot Cell. 2006 Dec;5(12):2033-46. Epub 2006 Oct 27.

A combined proteomic and transcriptomic approach to the study of stage differentiation in Leishmania infantum.
McNicoll F, Drummelsmith J, Müller M, Madore E, Boilard N, Ouellette M, Papadopoulou B.
Proteomics. 2006 Jun;6(12):3567-81.

2005


Distinct 3'-untranslated region elements regulate stage-specific mRNA accumulation and translation in Leishmania.
McNicoll FMüller M, Cloutier S, Boilard N, Rochette A, Dubé M, Papadopoulou B.
J Biol Chem. 2005 Oct 21;280(42):35238-46. Epub 2005 Aug 22.

2004


A coding mutation within the first exon of the human MD-2 gene results in decreased lipopolysaccharide-induced signaling.
Hamann L, Kumpf O, Müller M, Visintin A, Eckert J, Schlag PM, Schumann RR.
Genes Immun. 2004 Jun;5(4):283-8.