Orginalarbeiten (peer-reviewed) - Original papers


166. Y.N. Shi, S. Pusch, Y.M. Shi, C. Richter, J.G. Maciá-Vicente, H. Schwalbe, M. Kaiser, T. Opatz, H.B. Bode. (±)-Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus Alternaria alternata P1210 Isolated from the Halophyte Salicornia sp. J Org Chem. 2019 Aug 27. doi: 10.1021/acs.joc.9b01229. [Epub ahead of print]

165. L. Zhao, H.B. Bode. Production of a photohexapeptide library from entomopathogenic Photorhabdus asymbiotica PB68.1. Org Biomol Chem. 2019 Aug 12. doi: 10.1039/c9ob01489f. [Epub ahead of print]

164. Q. Zhou, A. Bräuer, H. Adihou, M. Schmalhofer, P. Saura, G.L.C. Grammbitter, V.R.I. Kaila, M. Groll, H.B. Bode. Molecular mechanism of polyketide shortening in anthraquinone biosynthesis of Photorhabdus luminescens. Chem Sci. 2019 May 14;10(25):6341-6349. doi: 10.1039/c9sc00749k. eCollection 2019 Jul 7.

163. D. Armaleo, O. Müller, F. Lutzoni, Ó.S. Andrésson, G. Blanc, H.B. Bode, F.R. Collart, F. Dal Grande, F. Dietrich, I.V. Grigoriev , S. Joneson, A. Kuo, P.E. Larsen, J.M. Logsdon Jr, D. Lopez, F. Martin, S.P. May, T.R. McDonald, S.S. Merchant, V. Miao, E. Morin, R. Oono, M. Pellegrini, N. Rubinstein, M.V. Sanchez-Puerta, E. Savelkoul, I. Schmitt, J.C. Slot, D. Soanes, P. Szövényi, N.J. Talbot, C. Veneault-Fourrey, B.B. Xavier. The lichen symbiosis re-viewed through the genomes of Cladonia grayi and its algal partner Asterochloris glomerata.
BMC Genomics. 2019 Jul 23;20(1):605. doi: 10.1186/s12864-019-5629-x.

162. R. Schmidt, D. Ulanova, L.Y. Wick, H.B Bode, P. Garbeva. Microbe-driven chemical ecology: past, present and future. ISME J. 2019 Jul 9. doi: 10.1038/s41396-019-0469-x. [Epub ahead of print] Review.

161. K.A.J. Bozhüyük, A. Linck, A. Tietze, J. Kranz, F. Wesche, S. Nowak, F. Fleischhacker,  Y.N. Shi, P. Grün, H.B. Bode. Modification and de novo design of non-ribosomal peptide synthetases using specific assembly points within condensation domains. Nat Chem. 2019 Jul;11(7):653-661. doi: 10.1038/s41557-019-0276-z. Epub 2019 Jun 10.

160. N.J. Tobias, C. Parra-Rojas, Y.N. Shi, Y.M. Shi, S. Simonyi, A. Thanwisai, A. Vitta, N. Chantratita, E.A. Hernandez-Vargas, H.B. Bode. Cyclo(tetrahydroxybutyrate) production is sufficient to distinguish between Xenorhabdus and Photorhabdus isolates in Thailand. Environ Microbiol. 2019 Aug;21(8):2921-2932. doi: 10.1111/1462-2920.14685. Epub 2019 Jun 10.

159. N.J. Tobias, H.B. Bode. Heterogeneity in Bacterial Spezialized Metabolism. J Mol Biol. 2019 May 6. pii: S0022-2836(19)30250-5. doi: 10.1016/j.jmb.2019.04.042. [Epub ahead of print] Review.

158. L. Drummond, M.J. Kschowak, J. Breitenbach, H. Wolff, Y.M. Shi, J. Schrader, H.B. Bode, G. Sandmann, M. Buchhaupt.
 Expanding the Isoprenoid Building Block Repertoire with an IPP Methyltransferase from Streptomyces monomycini. ACS Synth Biol. 2019 Jun 21;8(6):1303-1313. doi: 10.1021/acssynbio.8b00525. Epub 2019 May 14.

157. G.L.C. Grammbitter, M. Schmalhofer, K. Karimi, Y.M. Shi, T.A. Schöner, N.J. Tobias, N. Morgner, M. Groll, H.B. Bode. An Uncommon Type II PKS Catalyzes Biosynthesis of Aryl Polyene Pigments. Am Chem Soc. 2019 Apr 3. doi: 10.1021/jacs.8b10776. [Epub ahead of print]

156. Y.M. Shi, A.O. Brachmann, M.A. Westphalen, N. Neubacher, N.J. Tobias, H.B. Bode. Dual phenazine gene clusters enable diversification during biosynthesis. Nat Chem Biol. 2019 Apr;15(4):331-339. doi: 10.1038/s41589-019-0246-1. Epub 2019 Mar 18.

155. F. Wesche, H. Adihou, T.A. Wichelhaus, H.B. Bode. Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophilia. Beilstein J Org Chem. 2019 Feb 25;15:535-541. doi: 10.3762/bjoc.15.47. eCollection 2019.

154. X. Cai, L. Zhao, H.B. Bode. Reprogramming Promiscuous Nonribosomal Peptide Synthetases for Production of Specific Peptides. Org Lett. 2019 Apr 5;21(7):2116-2120. doi: 10.1021/acs.orglett.9b00395. Epub 2019 Mar 12.

153. K.A.B. Kissoyan , M. Drechsler, E.L. Stange, J. Zimmermann, C. Kaleta, H.B. Bode, K. Dierking. Natural C. elegans Microbiota Protects against Infection via Production of a Cyclic Lipopeptide of the Viscosin Group. Curr Biol. 2019 Mar 18;29(6):1030-1037.e5. doi: 10.1016/j.cub.2019.01.050. Epub 2019 Feb 28.

152. C. Reinheimer, D. Büttner, E. Proschak, H.B. Bode, V.A.J. Kempf, T.A. Wichelhaus. Anti-tubercular activity of a natural stilbene and its synthetic derivatives. GMS Infect Dis. 2018 Feb 1;6:Doc01. doi: 10.3205/id000036. eCollection 2018.

151. A. Calchera, F. Dal Grande, H.B. Bode, I. Schmitt. Biosynthetic Gene Content of the 'Perfume Lichens' Evernia prunastri and Pseudevernia furfuracea. Molecules. 2019 Jan 8;24(1). pii: E203. doi: 10.3390/molecules24010203.

150. S. Wenski, D. Kolbert, G. Grammbitter, H.B. Bode. Fabclavine biosynthesis in X. szentirmaii: shortened derivatives and characterization of the thioester reductase FclG and the condensation domain-like protein FclL. J Ind Microbiol Biotechnol. 2019 Jan 4. doi: 10.1007/s10295-018-02124-8. [Epub ahead of print]


149. C. Hacker, X. Cai, C. Kegler, L. Zhao, A.K. Weickhmann, J.P. Wurm, H.B. Bode, J. Wöhnert. Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. Nat Commun. 2018 Oct 19;9(1):4366. doi: 10.1038/s41467-018-06712-1.

148. L. Zhao, X. Cai, M. Kaiser, H.B. Bode. Methionine-Containing Rhabdopeptide/Xenortide-like Peptides from Heterologous Expression of the Biosynthetic Gene Cluster kj12ABC in Escherichia coli. J Nat Prod. 2018 Oct 26;81(10):2292-2295. doi: 10.1021/acs.jnatprod.8b00425. Epub 2018 Oct 10.

147. K.G. Thieme, J. Gerke, C. Sasse, O. Valerius, S. Thieme, R. Karimi, A. Heinrich, F. Finkernagel, K. Smith, H.B. Bode, M. Freitag, A.F.J. Ram, G.H. Braus. Correction: Velvet domain protein VosA represses the zinc cluster transcription factor SclB regulatory network for Aspergillus nidulans asexual development, oxidative stress response and secondary metabolism. PLoS Genet. 2018 Aug 29;14(8):e1007638. doi: 10.1371/journal.pgen.1007638. eCollection 2018 Aug.

146. L. Zhao, M. Kaiser, H.B. Bode. Rhabdopeptide/Xenortide-like Peptides from Xenorhabdus innexi with Terminal Amines Showing Potent Antiprotozoal Activity. Org Lett. 2018 Sep 7;20(17):5116-5120. doi: 10.1021/acs.orglett.8b01975. Epub 2018 Aug 10.

145. K.G. Thieme, J. Gerke, C. Sasse, O. Valerius, S. Thieme, R. Karimi, A. Heinrich, F. Finkernagel, K. Smith, H.B. Bode, M. Freitag, A.F.J. Ram, G. H. Braus. Velvet domain protein VosA represses the zinc cluster transcription factor SclB regulatory network for Aspergillus nidulans asexual development, oxidative stress response and secondary metabolism. PLoS Genet. 2018 Jul 25;14(7):e1007511. doi: 10.1371/journal.pgen.1007511. eCollection 2018 Jul. Erratum in: PLoS Genet. 2018 Aug 29;14(8):e1007638. 

144. N. Tobias, Y.M. Shi, H.B. Bode. Refining the Natural Product Repertoire in Entomopathogenic Bacteria. Trends Microbiol. 2018 Oct;26(10):833-840. doi: 10.1016/j.tim.2018.04.007. Epub 2018 May 22. Review.

143. F. Wesche, H. Adihou, A. Kaiser, M. Wurglics, M. Schubert-Zsilavecz, M. Kaiser, H.B. Bode. Combined Approach of Backbone Amide Linking and On-Resin N-Methylation for the Synthesis of Bioactive and Metabolically Stable Peptides. J Med Chem. 2018 May 10;61(9):3930-3938. doi: 10.1021/acs.jmedchem.7b01809. Epub 2018 Apr 20.

142. H. Wolff, H.B. Bode. The benzodiazepine-like natural product tilivalline is produced by the entomopathogenic bacterium Xenorhabdus eapokensis. PLoS One. 2018 Mar 29;13(3):e0194297. doi: 10.1371/journal.pone.0194297. eCollection 2018.

141. N. Tobias, A. Linck, H.B. Bode. Natural Product Diversification Mediated by Alternative Transcriptional Starting. Angew Chem Int Ed Engl. 2018 May 14;57(20):5699-5702. doi: 10.1002/anie.201713199. Epub 2018 Apr 14.

140. Y.M. Shi, C. Richter, V. Challinor, P. Grün, A. Girela Del Rio, M. Kaiser, A. Schüffler, M. Piepenbring, H. Schwalbe, H.B. Bode. Georatusin, a Specific Antiparasitic Polyketide-Peptide Hybrid from the Fungus Geomyces auratus. Org Lett. 2018 Mar 16;20(6):1563-1567. doi: 10.1021/acs.orglett.8b00293. Epub 2018 Feb 23.

139. K. Bozhüyük, F. Fleischhacker, A. Linck, F. Wesche, A. Tietze, C.P. Niesert, H.B. Bode. De novo design and engineering of non-ribosomal peptide synthetases. Nat Chem. 2018 Mar;10(3):275-281. doi: 10.1038/nchem.2890. Epub 2017 Dec 11.

138. J.G. Maciá-Vicente, Y.N. Shi, Z. Cheikh-Ali, P. Grün, K. Glynou, Kia S. Haghi, M. Piepenbring, H.B. Bode. Metabolomics-based chemotaxonomy of root endophytic fungi for natural products discovery. Environ Microbiol. 2018 Feb 14. doi: 10.1111/1462-2920.14072. [Epub ahead of print]


137. H. Pollmann, J. Breitenbach, H. Wolff, H.B. Bode, G. Sandmann. Combinatorial Biosynthesis of Novel Multi-Hydroxy Carotenoids in the Red Yeast Xanthophyllomyces dendrorhous. J Fungi (Basel). 2017 Feb 22;3(1). pii: E9. doi: 10.3390/jof3010009.

136. Y.M. Shi, H.B. Bode. Chemical language and warfare of bacterial natural products in bacteria-nematode-insect interactions. Nat Prod Rep. 2018 Jan 23. doi: 10.1039/c7np00054e. [Epub ahead of print] Review.

135. M. Gottardi, P. Grün, H.B. Bode, T. Hoffmann, W. Schwab, M. Oreb, E. Boles. Optimisation of trans-cinnamic acid and hydrocinnamyl alcohol production with recombinant Saccharomyces cerevisiae and identification of cinnamyl methyl ketone as a by-product. FEMS Yeast Res. 2017 Nov 23. doi: 10.1093/femsyr/fox091. [Epub ahead of print]

134. N.J. Tobias, H. Wolff, B. Djahanschiri, F. Grundmann, M. Kronenwerth, Y.M. Shi, S. Simonyi, P. Grün, D. Shapiro-Ilan, S.J. Pidot, T.P. Stinear, I. Ebersberger, H.B. Bode. Natural product diversity associated with the nematode symbionts Photorhabdus and Xenorhabdus. Nat Microbiol. 2017 Dec;2(12):1676-1685. doi: 10.1038/s41564-017-0039-9. Epub 2017 Oct 9.

133. E. Bode, Y. He, T.D. Vo, R. Schultz, M. Kaiser, H.B. Bode. Biosynthesis and function of simple amides in Xenorhabdus doucetiae. Environ Microbiol. 2017 Nov;19(11):4564-4575. doi: 10.1111/1462-2920.13919. Epub 2017 Oct 13.

132. P. Muangpat, T. Yooyangket, C. Fukruksa, M. Suwannaroj, T. Yimthin, S. Sitthisak, N. Chantratita, A. Vitta, N.J. Tobias, H.B. Bode, A. Thanwisai. Screening of the Antimicrobial Activity against Drug Resistant Bacteria of Photorhabdus and Xenorhabdus Associated with Entomopathogenic Nematodes from Mae Wong National Park, Thailand. Front Microbiol. 2017 Jun 28;8:1142. doi: 10.3389/fmicb.2017.01142. eCollection 2017.

131. A.K. Heinrich, M. Hirschmann, N. Neubacher, H.B. Bode. LuxS-dependent AI-2 production is not involved in global regulation of natural product biosynthesis in Photorhabdus and Xenorhabdus. PeerJ. 2017 Jun 26;5:e3471. doi: 10.7717/peerj.3471. eCollection 2017.

130. M. Hirschmann, F. Grundmann, H.B. Bode. Identification and occurence of the hydroxamate siderophores aerobactin, putrebactin, avaroferrin and ochrobactin C as virulence factors from entomopathogenic bacteria. Environ Microbiol. 2017 Oct;19(10):4080-4090. doi: 10.1111/1462-2920.13845. Epub 2017 Jul 21.

129. Y.M. Shi, H.B. Bode. Microbiology: A new language for small talk. Nat Chem Biol. 2017 Apr 13;13(5):453-454. doi: 10.1038/nchembio.2362. No abstract available.

128. F. Wesche, Y. He, H.B. Bode. Solid-phase enrichment and analysis of electrophilic natural products. Beilstein J Org Chem. 2017 Mar 2;13:405-409. doi: 10.3762/bjoc.13.43. eCollection 2017.

127. X. Cai, Y.M. Shi, N. Pöhlmann, O. Revermann, I. Bahner, S.J. Pidot, F. Wesche, H. Lackner, C. Büchel, M. Kaiser, C. Richter, H. Schwalbe, T.P. Stinear, A. Zeeck, H.B. Bode. Structure and Biosynthesis of Isatropolones. Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Gö66. Angew Chem Int Ed Engl. 2017 Apr 24;56(18):4945-4949. doi: 10.1002/anie.201701223. Epub 2017 Mar 30.

126. X. Cai, S. Nowak, F. Wesche, I. Bischoff, M. Kaiser, R. Fürst, H.B. Bode. Entomopathogenic bacteria use multiple mechanisms for bioactive peptide library design. Nat Chem. 2017 Apr;9(4):379-386. doi: 10.1038/nchem.2671. Epub 2016 Dec 5.

125. Y. Engel, C. Windhorst, X. Lu, H. Goodrich-Blair, H.B. Bode. The Global Regulators Lrp, LeuO, and HexA Control Secondary Metabolism in Entomopathogenic Bacteria. Front Microbiol. 2017 Feb 17;8:209. doi: 10.3389/fmicb.2017.00209. eCollection 2017.

124. X. Cai, V.L. Challinor, L. Zhao, D. Reimer, H. Adihou, P. Grün, M. Kaiser, H.B. Bode. Biosynthesis of the Antibiotic Nematophin and Its Elongated Derivatives in Entomopathogenic Bacteria. Org Lett. 2017 Jan 30. doi: 10.1021/acs.orglett.6b03796. [Epub ahead of print]

123. K.A. Bozhüyük, Q. Zhou, Y. Engel, A. Heinrich, A. Pérez, H.B. Bode. Natural Products from Photorhabdus and Other Entomopathogenic Bacteria. Curr Top Microbiol Immunol. 2017 Jan 4. doi: 10.1007/82_2016_24. [Epub ahead of print]

122. P. Kämpfer, N.J. Tobias, L.P. Ke, H.B. Bode, S.P. Glaeser. Xenorhabdus thuongxuanensis sp. nov. and Xenorhabdus eapokensis sp. nov., isolated from Steinernema species. Int J Syst Evol Microbiol. 2017 Jan 4. doi: 10.1099/ijsem.0.001770. [Epub ahead of print]


121. S.P. Glaeser, N.J. Tobias, A. Thanwisai, N. Chantratita, H.B. Bode, P. Kämpfer. Photorhabdus luminescens subsp. namnaonensis subsp. nov., isolated from Heterorhabditis baujardi nematodes in Nam Nao district of central Thailand. Int J Syst Evol Microbiol. 2016 Dec 29. doi: 10.1099/ijsem.0.001761. [Epub ahead of print]

120. A.K. Heinrich, A. Glaeser, N.J. Tobias, R. Heermann, H.B. Bode. Heterogeneous regulation of bacterial natural product biosynthesis via a novel transcription factor. Heliyon. 2016 Nov 29;2(11):e00197. eCollection 2016.

119. X. Cai, S. Nowak, F. Wesche, I. Bischoff, M. Kaiser, R. Fürst, H.B. Bode. Entomopathogenic bacteria use multiple mechanisms for bioactive peptide library design. Nature Chemistry(2016)doi:10.1038/nchem.2671

118. N.J. Tobias, T. Ahrendt, U. Schell, M. Miltenberger, H. Hilbi, H.B. Bode. Legionella shows a diverse secondary metabolism dependent on a broad spectrum Sfp-type phosphopantetheinyl transferase. PeerJ. 2016 Nov 24;4:e2720. PMID: 27904811.

117. F.S.Haack, A. Poehlein, C. Kröger, C.A. Voigt, M. Piepenbring, H.B. Bode, R. Daniel, W. Schäfer, W.R. Streit. Molecular Keys to the Janthinobacterium and Duganella spp. Interaction with the Plant Pathogen Fusarium graminearum. Front Microbiol. 2016 Oct 26;7:1668. PMID: 27833590

116. R.A. Orozco, I. Molnár, H.B. Bode, S.P. Stock. Bioprospecting for secondary metabolites in the entomopathogenic bacterium Photorhabdus luminescens subsp. sonorensis. J Invertebr Pathol. 2016 Nov;141:45-52. doi: 10.1016/j.jip.2016.09.008. PMID: 27702563

115. N.J. Tobias, A.K. Heinrich, H. Eresmann, P.R. Wright, N. Neubacher, R. Backofen, H.B. Bode. Photorhabdus-nematode symbiosis is dependent on hfq-mediated regulation of secondary metabolites. Environ Microbiol. 2016 Aug 23. doi: 10.1111/1462-2920.13502.

114.  N.J. Tobias, B. Mishra, D.K. Gupta, R. Sharma, M. Thines, T.P. Stinear, H.B. Bode. Genome comparisons provide insights into the role of secondary metabolites in the pathogenic phase of the Photorhabdus life cycle.
BMC Genomics.2016:17:537.doi:10.1186/s12864-016-2862-4.

113.  F. Hennicke, Z. Cheikh-Ali, T. Liebisch, J.G. Maciá-Vicente, H.B. Bode, M. Piepenbring. Distinguishing commercially grown Ganoderma lucidum from Ganoderma Lingzhi from Europe and East Asia on the basis of morphology, molecular phylogeny, and triterpenic acid profiles. Phytochemistry. 2016 Jul;127:29-37. doi: 10.1016/j.phytochem.2016.03.012.

112.  O. Schimming, I. Schmitt, H.B. Bode. Identification of the Sfp-Type PPTase EppA from the Lichenized Fungus Evernia prunastri. PLoS One. 2016 Jan 19;11(1):e0145624. doi: 10.1371/journal.pone.0145624. eCollection 2016.

111.  A.J. Pérez, F. Wesche, H. Adihou, H.B. Bode. Solid-Phase Enrichment and Analysis of Azide-Labeled Natural Products: Fishing Downstream of Biochemical Pathways. Chemistry. 2016 Jan 11;22(2):639-45. doi: 10.1002/chem.201503781. [Epub ahead of print]

110.  F. Barka, M. Angstenberger, T. Ahrendt, W. Lorenzen, H.B. Bode, C. Büchel. Identification of a triacylglycerol lipase in the diatom Phaeodactylum tricornutum. Biochim Biophys Acta. 2015 Dec 30;1861(3):239-248. doi: 10.1016/j.bbalip.2015.12.023. [Epub ahead of print]

109.  T. Schöner, S. Gassel, A. Osawa, N.J. Tobias, Y. Okuno, Y. Sakakibara, K. Shindo, G. Sandmann, H.B. Bode. Aryl polyenes, a highly abundant class of bacterial natural products, are functionally related to antioxidative carotenoids. Chembiochem. 2015 Dec 2. doi: 10.1002/cbic.201500474. [Epub ahead of print]


108.  G. Mulley, M.L. Beeton, P. Wilkinson, I. Vlisidou, N. Ockendon-Powell, A. Hapeshi, N.J. Tobias, F.I. Nollmann, H.B. Bode, J. van den Elsen, R.H. Ffrench-Constant, N.R.Waterfield . From Insect to Man: Photorhabdus Sheds Light on the Emergence of Human Pathogenicity. PLoS One. 2015 Dec 17;10(12):e0144937. doi: 10.1371/journal.pone.0144937. eCollection 2015.

107.  V.L. Challinor, H.B. Bode. Bioactive natural products from novel microbial sources. Ann N Y Acad Sci. 2015 Sep;1354(1):82-97.

106.  O. Schimming, V.L. Challinor, N.J. Tobias, H. Adihou, P. Grün, L. Pöschel, C. Richter, H. Schwalbe, H.B. Bode. Structure, Biosynthesis, and Occurrence of Bacterial Pyrrolizidine Alkaloids. Angew Chem Int Ed Engl. 2015, 54(43): 12702-5. doi: 10.1002/anie.201504877.

105.  R. Sharma, X. Xia, L.M. Cano, E. Evangelisti, E. Kemen, H. Judelson, S. Oome, C. Sambles, D.J. van den Hoogen, M. Kitner, J. Klein, H.J. Meijer, O. Spring, J. Win, R. Zipper, H.B. Bode, F. Govers, S. Kamoun, S. Schornack, D.J. Studholme, G. Van den Ackerveken, M. Thines. Genome analyses of the sunflower pathogen Plasmopara halstedii provide insights into effector evolution in downy mildews and Phytophthora. BMC Genomics. 2015;16(1):741.

104.  D. Kresovic, F. Schempp, Z. Cheikh-Ali, H.B. Bode. A novel and widespread class of ketosynthase is responsible for the head-to-head condensation of two acyl moieties in bacterial pyrone biosynthesis. Beilstein J Org Chem. 2015; 11:1412-7.

103. T. Ahrendt, C. Dauth, H.B. Bode. An iso-15:0 O-alkylglycerol moiety is the key structure of the E-signal in Myxococcus xanthus. Microbiology. 2015 Sep 4. doi: 10.1099/mic.0.000169.

102. Z. Cheikh-Ali, K. Glynou, T. Ali, S.Ploch, M. Kaiser, M. Thines, H.B. Bode, J.G. Maciiá-Vicente. Diversity of exophillic acid derivatives in strains of an endophytic Exophiala sp. Phytochemistry 2015, S0031-9422(15)30066-2

101. M.H. Medema, R. Kottmann, P. Yilmaz, M. Cummings, J.B. Biggins, K. Blin, I. de Bruijn, Y.H. Chooi, J. Claesen, R.C. Coates, P. Cruz-Morales, S. Duddela, S. Düsterhus, D.J. Edwards, D.P. Fewer, N. Garg, C. Geiger, J. P. Gomez-Escribano, A. Greule, M. Hadjithomas, A.S. Haines, E.J.  Helfrich, M.L. Hillwig, K. Ishida, A.C. Jones, C.S. Jones, K. Jungmann, C. Kegler, H.U. Kim, P. Kötter, D. Krug, J. Masschelein, A.V. Melnik, S.M. Mantovani, E.A. Monroe, M. Moore, N. Moss, H.W. Nützmann, G. Pan, A. Pati, D. Petras, F.J. Reen, F. Rosconi, Z. Rui, Z. Tian, N.J. Tobias, Y. Tsunematsu, P. Wiemann, E. Wyckoff, X. Yan, G. Yim, F. Yu, Y. Xie, B. Aigle, A. K. Apel, C.J. Balibar, E.P. Balskus, F. Barona-Gómez, A. Bechthold, H.B. Bode, R. Borriss, S.F. Brady, A.A. Brakhage, P. Caffrey, Y.Q. Cheng, J. Clardy, R.J. Cox, R. De Mot, S. Donadio, M.S. Donia, W.A. van der Donk, P.C.Dorrestein, S. Doyle, A.J. Driessen, M. Ehling-Schulz, K.D. Entian, M.A. Fischbach, L. Gerwick, W.H. Gerwick, H. Gross, B. Gust, C. Hertweck, M. Höfte, S.E. Jensen, J. Ju, L. Katz, L. Kaysser, J.L. Klassen, N.P. Keller, J. Kormanec, O.P. Kuipers, T. Kuzuyama, N.C. Kyrpides, H.J. Kwon, S. Lautru, R. Lavigne, C.Y. Lee, B. Linquan, X. Liu, W. Liu, A. Luzhetskyy, T. Mahmud, Y. Mast, C. Méndez, M. Metsä-Ketelä, J. Micklefield, D.A. Mitchell, B.S. Moore, L.M. Moreira, R. Müller, B.A. Neilan, M. Nett, J. Nielsen, F. O'Gara, H. Oikawa, A. Osbourn, M.S. Osburne, B. Ostash, S.M. Payne, J.L. Pernodet, M. Petricek, J. Piel, O. Ploux, J.M. Raaijmakers, J.A. Salas, E.K. Schmitt, B. Scott, R.F. Seipke, B. Shen, D.H. Sherman, K. Sivonen, M.J. Smanski, M. Sosio, E. Stegmann, R.D. Süssmuth, K. Tahlan, C.M. Thomas, Y. Tang, A.W. Truman, M. Viaud, J.D. Walton, C.T. Walsh, T. Weber, G.P. van Wezel, B. Wilkinson, J.M. Willey, W. Wohlleben, G.D. Wright, N. Ziemert, C. Zhang, S.B. Zotchev, R. Breitling, E. Takano, F.O. Glöckner. Minimum information about a Biosynthetic Gene cluster. Nat Chem Biol 2015, 11(9): 625-632

100. T. Schöner, D. Kresovic, H.B. Bode. Biosynthesis and function of bacterial dialkylresorcinol compounds. Appl Microbiol Biotechnol 2015, [Epub ahead of print]

99. S. Brameyer, H.B. Bode, R. Heermann. Languages and dialects: bacterial communication beyond homoserine lactones. Trends Microbiol. 2015, [Epub ahead of print]

98. H.B. Bode. The Microbes inside Us and the Race for Colibactin. Angew Chem Int Ed Engl. 2015, [Epub ahead of print]

97. T. Ahrendt, H. Wolff, H.B. Bode. The lipidome of neutral and phospholipids of Myxococcus xanthus during fruiting body formation and germination. Appl Environ Microbiol. 2015, 01537-15

96. H. B. Bode, A. O. Brachmann, K. B. Jadhav, L. Seyfarth, C. Dauth, S. W. Fuchs, M. Kaiser, N. R. Waterfield, H. Sack, S. H. Heinemann, H. D. Arndt. Structure Elucidation and Activity of Kolossin A, the D-/L-Pentadecapeptide Product of a Giant Nonribosomal Peptide Synthetase. Angew Chem int Ed Engl. 2015, [Epub ahead of print]

95. A. Perez, H. B. Bode. "Click-chemistry" for the simple determination of fatty acid uptake and degradation - Revising the role of fatty acid transporters. Chembiochem. 2015, [Epub ahead of print] 

94. E. Bode, A. O. Brachmann, C. Kegler, R. Simsek, C. Dauth, Q. Zhou, M. Kaiser, P. Klemmt, H. B. Bode. Simple “On-Demand" Production of Bioactive Natural Products. Chembiochem. 2015, 16(7): 1115-1119 

93. N. J. Tobias, B. Mishra, D. K. Gupta, L. P. Ke, M. Thines, H. B. Bode. Draft Genome Sequence of Ochrobactrum anthropi Strain ML7 Isolated from Soil Samples in Vinhphuc Province, Vietnam. Genome Announc. 2015, 3 (2)

92. F. I. Nollmann, A. K. Heinrich, A. O. Brachmann, C. Morisseau, K. Mukherjee, Ý. M. Casanova-Torres, F. Strobl, D. Kleinhans, S. Kinski, K. Schultz, M. L. Beeton, M. Kaiser, Y. Chu, L. Phan Ke, A. Thanwisai, K. A. J. Bozhüyük, N. Chantratita, F. Gçtz, N. R. Waterfield, A. Vilcinskas, E. H. K. Stelzer, H. Goodrich-Blair, B. D. Hammock, H. B. Bode. A Photorhabdus Natural Product Inhibits Insect Juvenile Hormone Epoxide Hydrolase. Chembiochem. 2015, 16(5): 766-771

91. S. Brameryer, D. Kresovic, H. B. Bode, R. Herrmann. Dialkylresorcinols as bacterial signaling molecules. PNAS 2015, 112, 572-577

90. F. I. Nollmann, C. Dauth, G. Mulley, C. Kegler, M. Kaiser, N. R. Waterfield, H. B. Bode. Insect-specific production of new GameXPeptides in photorhabdus luminescens TTO1, widespread natural products in entomopathogenic bacteria. Chembiochem. 2015, 16(2): 205-208

89. K. Schuchmann, S. Schmidt, A. Martinez Lopez, C. Kaberline, M. Kuhns, W. Lorenzen, H. B. Bode, F. Joos, V. Müller. Nonacetogenic growth of the acetogen Acetobacterium woodii on 1,2-propanediol. J Bacteriol. 2015, 197(2): 382-391


88. M. Kronenwerth, C. Dauth, M. Kaiser, I. Pemberton, H. B. Bode. Facile Synthesis of Cyclohexanediones and Dialkylresorcinols – Bioactive Natural Products from Entomopathogenic Bacteria. Eur. J. Org. Chem. 2014, [Epub ahead of print]

87. M. Kronenwerth, K. A. Bozhüyük, A. S. Kahnt, D. Steinhilber, S. Gaudriault, M. Kaiser, H. B. Bode. Characterisation of Taxlllaids A-G; Natural Products from Xenorhabdus indica. Chemistry. 2014, 20(52): 17478-17487

86. M. Kronenwerth, A. O. Brachmann, M. Kaiser, H. B. Bode. Bioactive Derivatives of Isopropylstilbene from Mutasynthesis and Chemical Synthesis. Chembiochem. 2014, 15(18):2689-2691

85. W. Lorenzen, K. A. Bozhüyük, N. S. Cortina, H. B. Bode. A comprehensive insight into the lipid composition of Myxococcus xanthus by UPLC ESI-MS. J Lipid Res. 2014, 55(12):2620-2633

84. D. Reimer, F. I. Nollmann, K. Schultz, M. Kaiser, H. B. Bode. Xenortide Biosynthesis by Entomopathogenic Xenorhabdus nematophila. J Nat Prod. 2014, [Epub ahead of print]

83. A. J. Perez, H. B. Bode. ω-Azido fatty acids as probes to detect fatty acid biosynthesis, degradation, and modification. J Lipid Res. 2014, 55(9):1897-1901

82. B. I. Morinaka, A. L. Vagstad, M. J. Helf, M. Gugger, C. Kegler, M. F. Freeman, H. B Bode and J. Piel. Radical S-Adenosyl Methionine Epimerases: Regioselective Introduction of Diverse D-Amino Acid Patterns into Peptide Natural Products. Angew. Chem. Int. Ed. 2014, 53(32):8503-8507.

81. W. Lorenzen, T. Ahrendt, K. A. J. Bozhüyük and H. B Bode. A multifunctional enzyme is involved in bacterial ether lipid biosynthesis. Nat. Chem. Biol. 2014, 10(6):425-427

80. O. Schimming, F. Fleischhacker, F. I. Nollmann, and H.B. Bode. Yeast Homologous Recombination Cloning Leading to the Novel Peptides Ambactin and Xenolindicin. ChemBioChem, 2014, 15(9):1290-1294.

79. F. Grundmann, M. Kaiser, M. Schiell, A. Batzer, M. Kurz, A. Thanwisai, N. Chantratita, H. B. Bode. Antiparasitic Chaiyaphumines from Entomopathogenic Xenorhabdus sp. PB61.4. J Nat Prod. 2014, 77(4):779-783.

78. C. Kegler, F. I. Nollmann, T. Ahrendt, F. Fleischhacker, E. Bode, H. B. Bode. Rapid Determination of the Amino Acid Configuration of Xenotetrapeptide. ChemBioChem, 2014, 15(6):826-8.

77. T. A. Schöner, S. W. Fuchs, B. Reinhold-Hurek, H. B.  Bode. Identification and Biosynthesis of a Novel Xanthomonadin-Dialkylresorcinol-Hybrid from Azoarcus sp. BH72. PLoS ONE. 2014. 9:e90922.

76. S. W. Fuchs, F. Grundmann, M. Kurz, M. Kaiser, H. B. Bode. Fabclavines: bioactive peptide-polyketide-polyamino hybrids from Xenorhabdus. Chembiochem. 2014, 15(4): 512-516.

75. H. Schild, S. W. Fuchs, H. B. Bode*, B. Grünewald*, Low-molecular weight metabolites secreted by Paenibacillus larvae as potential virulence factors of American Foulbrood,  Appl. Environ. Microbiol. 2014, 80(8):2484-2492.

74.  S. Bhat, T. Ahrendt, C. Dauth, H. B. Bode, L. J. Shimkets*, Two lipid signals guide fruiting body development of Myxococcus xanthus, mBio 2014, 5(1):e00939-13.

73.  A. Proschak, Q. Zhou, T. Schöner, A. Thanwisai, D. Kresovic, A. Dowling, R. ffrench-Constant, E. Proschak, H. B. Bode*, Biosyntheis of the Insecticidal Xenocyloins in Xenorhabdus bovienii,  ChemBioChem, 2014, 15(3):369-372.

72.  T.A. Schöner, S. W. Fuchs, C. Schönau, H. B. Bode*, Initiation of the flexirubin biosynthesis in Chitinophaga pinensisMicrob Biotechnol. 2014, 7(3):232-241.

71. D. Reimer, H. B. Bode. A natural prodrug activation mechanism in the biosynthesis of nonribosomal peptides, Nat Prod Rep. 2014, 31(2): 154-159.


70.  L. Lango-Scholey, A. O. Brachmann, H. B. Bode, D. Clarke*, The expression of stlA in Photorhabdus luminescens is controlled by nutrient limitation, PLoS ONE 2013, 8: e82152.

69.  Q. Zhou, F. Grundmann, M. Kaiser, M. Schiell, S. Gaudriault, A. Batzer, M. Kurz, H. B. Bode*, Structure and biosynthesis of xenoamicines from entomopathogenic Xenohabdus, Chem. Eur. J. 2013, 19, 16772-16779.

68.  F. Grundmann, M. Kaiser, M. Kurz, M. Schiell, A. Batzer, H. B. Bode*, Structure determination of the bioactive depsipeptide xenobactin from Xenorhabdus sp. PB30.3, RSC Advance 2013, 3, 22072-22077.

67.  D. Reimer, K. N. Cowles, A. Proschak, F. I. Nollmann, A. J. Dowling, M. Kaiser, R. ffrench-Constant, H. Goodrich-Blair, H. B. Bode*, Rhabdopeptides as insect-specific virulence factors from entomopathogenic bacteria, ChemBioChem 2013, 14, 1991-1997.

66.  A. O. Brachmann, S. Brameyer, D. Kresovic, I. Hiltkova, Y. Kopp, C. Manske, K. Schubert, H. B. Bode*, R. Heermann*, Pyrones as bacterial signaling molecules, Nat. Chem. Biol. 2013, 9, 573-578.

65.  T. Ahrendt, M. Miltenberger, I. Haneburger, F. Kirchner, M. Kronenwerth, A. O. Brachmann, H. Hilbi, H. B. Bode*, Biosynthesis of the natural fluorophore legioliulin from Legionella, ChemBioChem, 2013, 14, 1415-1418.

64.  F. Sahm, I. Oezen, C.A. Opitz, B. Radlwimmer, A. von Deimling, T. Ahrendt, S. Adams, H.B. Bode, G.J. Giullemin, W. Wick, M. Platten*, The endogenous tryptophan metabolite and NAD+ precursor Quinolinic acid confers resistance of gliomas to oxidative stress, Cancer Res. 2013, 73, 3225-3234.

63.  A. Proschak, P. Lubuta, P. Grün, F. Löhr, G. Wilharm, V. De Berardinis, H.B. Bode*, Structure and biosynthesis of fimsbactins A-F, siderophores from Acinetobacter baumannii and Acinetobacter baylyi, Chembiochem. 2013, 14, 633-638.

62.  S.W. Fuchs, K.A.J. Bozhüyük, D. Kresovic, F. Grundmann, V. Dill, A.O. Brachmann, N.R. Waterfield, H.B. Bode*, Formation of 1,3-Cyclohexanediones and Resorcinols Catalyzed by a Widely Occuring Ketosynthase. Angew. Chem. Int. Ed. 2013, 52, 4108-4112.

61.  E. Buscató, D. Büttner, A. Brüggerhoff, F.-M. Klingler, J. Weber, B. Scholz, A. Živković, R. Marschalek, H. Stark, D. Steinhilber, H.B. Bode, E. Proschak*, From a Multipotent Stilbene to Soluble Epoxide Hydrolase Inhibitors with Antiproliferative Properties, ChemMedChem, 2013, 8, 919-923.

60.  C. Hornung, A. Poehlein, F.S. Haack, M. Schmidt, K. Dierking, A. Pohlen, H. Schulenburg, M. Blokesch, L. Plener, K. Jung, A. Bonge, I. Krohn-Molt, C. Utpatel, G. Timmermann, E. Spieck, A. Pommerening-Röser, E. Bode, H.B. Bode, R. Daniel, C. Schmeisser, W.R. Streit*, The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases, PLoS ONE, 2013, 8(2):e55045.


59.  Q. Zhou, A. Dowling, H. Heide, J. Wöhnert, U. Brandt, J. Baum, R. ffrench-Constant, H.B. Bode*, Xentrivalpeptides A-Q: Depsipeptide diversification in Xenorhabdus, J. Nat. Prod. 2012, 75, 1717-1722.

58.  D. Brat, C. Weber, W. Lorenzen, H.B. Bode, E. Boles*, Cytosolic re-localization and optimization of valine synthesis and catabolism enables increased isobutanol production with the yeast Saccharomyces cerevisiae, Biotechnol. Biofuels, 2012, 5, 65.

57.  A.O. Brachmann, D. Reimer, W. Lorenzen, E. Augusto Alonso, Y. Kopp, J. Piel, H.B. Bode*, Reciprocal crosstalk between fatty acid and antibiotic biosynthesis in a nematode symbiont, Angew. Chem. Int. Ed. 2012, 51, 12086-12089.

56.  F. Hilbers, J. van Wonderen, W. Lorenzen, H.B. Bode, F. MacMillan, B. Ludwig, H. Michel*, The catalase activity of the aa3 cytochrome c oxidase from Paracoccus denitrificans, Biochim. Biophys. Acta (BBA) – Bioenergetics, 2012, 187, S108.

55.  A. Thanwisai, S. Tandhavanant, N. Saiprom, N.R. Waterfield, L. Phan Ke, H.B. Bode, S.J. Peacock, N. Chantratita*, Diversity of Xenorhabdus and Photorhabdus spp. and their symbiotic entomopathogenic nematodes from Thailand, PLoS ONE, 2012, 7, e43835.

54.  S.W. Fuchs, C.C. Sachs, C. Kegler, F.I. Nollmann, M. Karas, H.B. Bode*, Neutral loss fragmentation pattern based screening for arginine-rich natural products in Xenorhabdus and Photorhabdus, Anal. Chem., 2012, 84, 6948-6955.

53.  F. Grundmann, V. Dill, A. Dowling, A. Thanwisai, E. Bode, N. Chantratita, R. ffrench-Constant, H.B. Bode*, Identification and isolation of insecticidal oxazoles from Pseudomonas sp., Beilstein J. Org. Chem., 2012, 8, 749-752.

52.  F.I. Nollmann, A. Dowling, M. Kaiser, K. Deckmann, S. Grösch, R. ffrench-Constant, H.B. Bode*, Synthesis of szentiamide, a depsipeptide from entomopathogenic Xenorhabdus szentirmaii with activity against Plasmodium falciparum, Beilstein J. Org. Chem., 2012, 8, 528-533.

51.  H.B. Bode*, D. Reimer, S.W. Fuchs, F. Kirchner, C. Dauth, C. Kegler, W. Lorenzen, A.O. Brachmann, P. Grün, Determination of the absolute configuration of peptide natural products using stable isotope labeling and mass spectrometry, Chem. Eur. J., 2012, 18, 2342-2348.

50.  J.M. Chaston, G. Suen, S.L. Tucker, A.W. Andersen, A. Bhasin, E. Bode, H.B. Bode, A.O. Brachmann, C.E. Cowles, K.N. Cowles, C. Darby, L. de Léon, K. Drace, Z. Du, A. Givaudan, E.E. Herbert Tran, K.A. Jewell, J.J. Knack, K.C. Krasomil-Osterfeld, R. Kukor, A. Lanois, P. Latreille, N.K. Leimgruber, C.M. Lipke, R. Liu, X. Lu, E.C. Martens, P. R. Marri, C. Médigue, M.L. Menard, N.M. Miller, N. Morales-Soto, S Norton, J.-C. Ogier, S.S. Orchard, D. Park,Y. Park, B.A. Qurollo, D. Renneckar Sugar, G.R. Richards, Z. Rouy, B. Slominski, K. Slominski, H. Snyder, B.C. Tjaden, R. van der Hoeven, R.D. Welch, C. Wheeler, B. Xiang, B. Barbazuk, S. Gaudriault, B. Goodner, S.C. Slater, S. Forst, B.S. Goldman*, H. Goodrich-Blair*, The Entomopathogenic Bacterial Endosymbionts Xenorhabdus and Photorhabdus: Convergent Lifestyles from Divergent Genomes, PLoS ONE, 2011, 6, e27909.

49.  A.O. Brachmann, F. Kirchner, C. Kegler, S.W. Kinski, I. Schmitt, H.B. Bode*, Triggering the production of the cryptic blue pigment indigoidine from Photorhabdus luminescens. J. Biotechnol. 2012, 157, 96-99.


48.  D. Reimer, K.M. Pos, M. Thines, P. Grün, H.B. Bode*, A natural prodrug activation mechanism in nonribosomal peptide synthesis. Nat. Chem. Biol. 2011, 7, 888-890.

47.  A. Proschak, K. Schultz, J. Herrmann, A.J. Dowling, A.O. Brachmann, R. ffrench-Constant, R. Müller, H.B. Bode*, Cytotoxic fatty acid amides from Xenorhabdus. ChemBioChem 2011, 12, 2011-2015.

46.  M. Kopp, H. Irschik, K. Gemperlein, K. Buntin, P. Meiser, K.J. Weissman, H.B. Bode, R. Müller*, Insights into the complex biosynthesis of the leupyrrins in Sorangium cellulosum So ce690. Mol. Biosyst. 2011, 7, 1549-1563.

45.  S.W. Fuchs, A. Proschak, T.W. Jaskolla, M. Karas, H.B. Bode*, Structure elucidation and biosynthesis of lysine-rich cyclic peptides in Xenorhabdus nematophila. Org. Biomol. Chem. 2011, 9, 3130-3132.


44.  E. Hoiczyk*, M.W. Ring, C.A. McHugh, G. Schwär, E. Bode, D. Krug, M.O. Altmeyer, J.Z. Lu, H.B. Bode*, Lipid body formation plays a critical role in cell fate determination during developmental differentiation of Myxococcus xanthus. Mol. Microbiol. 2009, 74, 497-517.

43.  D. Park, K. Ciezki, R. van der Hoeven, S. Singh, D. Reimer, H.B. Bode, S. Forst*, Genetic analysis of xenocoumacin antibiotic production in the mutualistic bacterium Xenorhabdus nematophila, Mol. Microbiol., 2009, 73, 938-949.

42.  D. Reimer, E. Luxenburger, A.O. Brachmann, H.B. Bode*, A new type of pyrrolidine biosynthesis is involved in the late steps of xenocoumacin production in Xenorhabdus nematophila, ChemBioChem 2009, 10, 1997-2010.

41.  W. Lorenzen, G. Schwär, R. Müller, H.B. Bode*, Isoprenoids are required for fruiting body formation in M. xanthus, J. Bacteriol. 2009, 191. 5849-5853.

40.  M.W. Ring, G. Schwär, H.B. Bode*, Biosynthesis of 2‑hydroxy and iso‑even fatty acids is connected to sphingolipid formation in myxobacteria, ChemBioChem 2009, 10, 2003-2010.

39.  M.W. Ring, E. Bode, G. Schwär, H.B. Bode*, Functional analysis of desaturases from the myxobacterium Myxococcus xanthus, FEMS Microbiol. Lett. 2009, 296, 124-130.

38.  A. Zöllner, C.A. Dragan, D. Pistorius, R. Müller, H.B. Bode, F.T. Peters, H.H. Maurer, M. Bureik, Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid, Biol. Chem. 2009, 390, 313-317.

37.  B. Ohlendorf, W. Lorenzen, S. Kehraus, A. Krick, H.B. Bode, G.M. König*, Myxotyrosides A and B, unusual Rhamnosides from Myxococcus sp., J. Nat. Prod. 2009, 72, 82-86.

36.  H.B. Bode, M.W. Ring, G. Schwär, M.O. Altmeyer, C. Kegler, I.R. Jose, M. Singer, R. Müller*, Identification of additional players in the alternative biosynthesis pathway to isovaleryl-CoA in the myxobacterium Myxococcus xanthus, ChemBioChem 2009, 10, 128-140.


35.  N.R. Waterfield*, M. Sanchez-Contreras, I. Eleftherianos, A. Dowling, P. Wilkinson, J. Parkhill, N. Thomson, S.E. Reynolds, H.B. Bode, S. Dorus, R.H. ffrench-Constant, Rapid Virulence Annotation (RVA): Identification of virulence factors using a bacterial genome library and multiple invertebrate hosts, Proc. Natl. Acad. Sci. USA 2008, 105, 15967-15972.

34.  S.C. Wenzel, H.B. Bode, I. Kochems, R. Müller*, A type I/type III polyketide synthase hybrid biosynthetic pathway for the structurally unique ansa compound kendomycin, ChemBioChem 2008, 9, 2711-2721.

33.  P. Meiser, K.J. Weissman, H.B. Bode, J.S. Dickschat, A. Sandmann, R. Müller*, DKxanthene biosynthesis – Understanding the basis for diversity-oriented synthesis in myxobacterial secondary metabolism, Chem. Biol. 2008, 15, 771-781.

32.  S.A. Joyce, A.O. Brachmann, I. Glazer, L. Lango, G. Schwär, D.J. Clarke*, H.B. Bode*, Bacterial biosynthesis of a multipotent stilbene, Angew. Chem. Int. Ed. 2008, 47, 1942-1945. (ausgewählt als VIP-Paper).


31.  S. Schneiker, O. Perlova, A. Alici, M.O. Altmeyer, D. Bartels, T. Bekel, S. Beyer, H. Blöcker, E. Bode, H.B. Bode, C. Bolten, J.V. Choudhuri, S. Doss, Y.A. Elnakady, B. Frank, L. Gaigalat, K. Gerth, A. Goesmann, C. Groeger, F. Gross, L. Jelsbak, L. Jelsbak, O. Kaiser, J. Kalinowski, C. Kegler, T. Knauber, S. Konietzny, M. Kopp, L. Krause, D. Krug, B. Linke, T. Mahmud, R. Martinez-Arias, A.C. McHardy, M. Merai, F. Meyer, S. Mormann, J. Munoz-Dorado, J. Perez, S. Rachid, G. Raddatz, F. Rosenau, C. Rückert, F. Sasse, M. Scharfe, S.C. Schuster, G. Suen, A. Treuner-Lange, G.J. Velicer, F.-J. Vorhölter, K.J. Weissman, R.D. Welch, S.C. Wenzel, D. Whitworth, S. Wilhelm, C. Wittmann, A. Pühler, R. Müller*, Complete sequence of the largest known bacterial genome from the myxobacterium Sorangium cellulosum, Nature Biotechnol. 2007, 25, 1281-1289.

30.  B. Frank, S.C Wenzel, H.B. Bode, M. Scharfe; H. Blöcker, R. Müller*, From genetic diversity to metabolic unity: studies on the biosynthesis of aurafurones and aurafuron-like structures in myxobacteria and streptomycetes, J. Mol. Biol. 2007, 374, 24-38.

29.  H.B. Bode*, P. Meiser, T. Klefisch, N. Socorro d. J. Cortina, D. Krug, A. Göhring, G. Schwär, T. Mahmud, Y.A. Elnakady, R. Müller*, Mutasynthesis-derived myxalamids and origin of the isobutyryl-CoA starter unit of myxalamid B, ChemBioChem 2007, 8, 2139-2144.

28.  P. Latreille, S. Norton, B.S. Goldman, J. Henkhaus, N. Miller, B. Barbazuk, H.B. Bode, C. Darby, Z. Du, S. Forst, S. Gaudriault, B. Goodner, H. Goodrich-Blair, S. Slater*, Optical Mapping as a Routine Tool for Bacterial Genome Sequence Finishing, BMC Genomics 2007, 8, 321.

27.  A.O. Brachmann, S.A. Joyce, H. Jenke-Kodama, G. Schwär, D.J. Clarke, H.B. Bode*, A type II polyketide synthase is responsible for anthraquinone biosynthesis in Photorhabdus luminescens, ChemBioChem 2007, 8, 1721-1728.


26.  A.O. Brachmann, S. Forst, G.M. Furgani, A. Fodor, H.B. Bode*, Xenofuranones A and B: Phenylpyruvate dimers from Xenorhabdus szentirmaii, J. Nat. Prod. 2006, 69, 1830-1832.

25.  P. Meiser, H.B. Bode, R. Müller*, The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulation, Proc. Natl. Acad. Sci. USA 2006, 103, 19128-33.

24.  M.W. Ring, G. Schwär, V. Thiel, J.S. Dickschat, R.M. Kroppenstedt, S. Schulz, H.B. Bode*, Novel iso-branched etherlipids as specific markers of developmental sporulation in the myxobacterium Myxococcus xanthus, J. Biol. Chem. 2006, 281,36691-36700.

23.  H.B. Bode*, M.W. Ring, G. Schwär, R.M. Kroppenstedt, D. Kaiser, R. Müller*, 3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in the biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation, J. Bacteriol. 2006, 188, 6524-6528.

22.  H.B. Bode*, M.W. Ring, D. Kaiser, A.C. David, R.M. Kroppenstedt, G. Schwär, Straight-chain fatty acids are dispensable in the myxobacterium Myxococcus xanthus, J. Bacteriol. 2006, 188, 5632-5634.


21.  J. S. Dickschat, H.B. Bode, T. Mahmud, R. Müller, S. Schulz*, A novel type of Geosmin biosynthesis in myxobacteria, J. Org. Chem. 2005, 70, 5174-82.

20.  J. S. Dickschat, H.B. Bode, R. M. Kroppenstedt, R. Müller, S. Schulz*, Biosynthesis of iso-fatty acids in myxobacteria, Org. Biomol. Chem. 2005, 3, 2824-31.

19.  J.S. Dickschat, H.B. Bode, S.C. Wenzel, R. Müller, S. Schulz*, Biosynthesis and Identification of Volatiles Released by the Myxobacterium Stigmatella aurantiaca, ChemBioChem 2005, 6, 2023-2033.

18.  H.B. Bode, J.S. Dickschat, R.M. Kroppenstedt, S. Schulz, R. Müller*, Biosynthesis of iso-fatty acids in myxobacteria: iso-even fatty acids are derived from a-oxidation of iso-odd fatty acids, J. Am. Chem. Soc., 2005, 127, 532-533.

17.  T. Mahmud, S.C. Wenzel, E. Wan, K.W. Wen, H.B. Bode, N. Gaitatzis, R. Müller*, A Novel Biosynthetic Pathway to Isovaleryl-CoA in Myxobacteria: The Involvement of the Mevalonate Pathway, ChemBioChem, 2005, 6, 322-330.


16.  S.C. Wenzel, H.B. Bode*, Novel polyene carboxylic acids from Streptomyces, J. Nat. Prod., 2004, 67, 1631-1633.

15.  H.B. Bode, S.C. Wenzel, H. Irschik, G. Höfle, R. Müller*, An unusual biosynthesis leading to the unique leupyrrin class of natural products in the myxobacterium Sorangium cellulosum, Angew. Chem. Int Ed Engl 2004., 43, 4163-4167.

14.  J.S. Dickschat, S.C. Wenzel, H.B. Bode, T. Mahmud, R. Müller*, S. Schulz*, Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus, ChemBioChem, 2004, 5, 778-787.


13.  H.B. Bode, H. Irschik, S.C. Wenzel, H. Reichenbach, R. Müller, G. Höfle*, The Leupyrrins: a structurally unique family of secondary metabolites from the myxobacterium Sorangium cellulosum, J. Nat. Prod., 2003, 66, 1203-1206.

12.  H.B. Bode, B. Zeggel, B. Silakowski, S.C. Wenzel, H. Reichenbach, R. Müller*, Steroid biosynthesis in prokaryotes: Identification of myxobacterial steroids and cloning of the first bacterial 2,3(S)-oxidosqualene cyclase from the myxobacterium Stigmatella aurantiaca, Mol. Microbiol, 2003, 47, 471-481.

11.  S. Busch, H.B. Bode, A.A. Brakhage, G.H. Braus*, Impact of the cross-pathway control on the metabolic flux towards lysine and penicillin in Aspergillus nidulans, Curr. Genetics, 2003, 42, 209-219.


10.  T. Mahmud, H.B. Bode, B. Silakowski, R.M. Kroppenstedt, M. Xu, S. Nordhoff, G. Höfle, R. Müller*, A novel biosynthetic pathway providing precursors for fatty acid biosynthesis and secondary metabolite formation in myxobacteria, J. Biol. Chem., 2002, 277, 32768-32774.


9.    H.B. Bode, K. Kerkhoff, D. Jendrossek*, Bacterial degradation of natural and synthetic rubber, Biomacromolecules, 2001, 2, 295-303.


8.    H.B. Bode, A. Zeeck, K. Plückhahn, D. Jendrossek*, Physiological and chemical investigations into microbial degradation of synthetic poly(cis-1,4-isoprene), Appl. Environ. Microbiol., 2000, 66, 3680-3685.

7.    H.B. Bode, A. Zeeck*, Structure and biosynthesis of kendomycin, a carbocyclic ansa-compound from Streptomyces, J. Chem. Soc., Perkin Trans. 1, 2000, 323-328.

6.    H.B. Bode, A. Zeeck*, Biosynthesis of kendomycin: Origin of the oxygen atoms and further investigations, J. Chem. Soc., Perkin Trans. 1, 2000, 2665-2670.

5.    H.B. Bode, B. Wegner, A. Zeeck*, Biosynthesis of cladospirone bisepoxide, a member of the spirobisnaphthalene family, J. Antibiotics, 2000, 53, 153-157.

4.    H.B. Bode, A. Zeeck*, Sphaerolone and dihydrosphaerolone, two bisnaphthyl-pigments from the fungus Sphaeropsidales sp. F-24´707, Phytochemistry, 2000, 54, 597-601.

3.    H.B. Bode, A. Zeeck*, UV mutagenesis and enzyme inhibitors as tools to elucidate the late biosynthesis of the spirobisnaphthalenes, Phytochemistry, 2000, 55, 311-316.

2.    H.B. Bode, M. Walker, A. Zeeck*, Structure and biosynthesis of mutolide, a novel macrolide from a UV mutant of the fungus F-24´707, Eur. J. Org. Chem., 2000, 1451-1456.

1.    H.B. Bode, M. Walker, A. Zeeck*, Cladospirones B to I from Sphaeropsidales sp. F-24´707 by variation of culture conditions, Eur. J. Org. Chem., 2000, 3185-3193.

Übersichtsartikel und Buchkapitel (peer-reviewed)/ Reviews and book chapters

10.  A.O. Brachmann, H.B. Bode*, Identification and bioanalysis of natural products from insect symbionts and pathogens (Chapter 2.3) in: Adv. Biochem. Eng. Biotechnol. Vilcinskas, A. (Ed.) Yellow Biotechnology, Springer, 2013 (im Druck).

9.    H.B. Bode*, Insect-Associated Microorganisms as a Source for Novel Secondary Metabolites with Therapeutic Potential (Chapter 5) in: Vilcinskas, A. (Ed.) Insect Biotechnology, Springer, 2010, 77-93.

8.    H.B. Bode*, Entomopathogenic bacteria as source of new secondary metabolites, Curr. Opin. Chem. Biol. 2009, 13, 224-230.

7.    H.B. Bode*, Insects: True pioneers in anti-infective therapy and what we can learn from them, Angew. Chem. Int. Ed. 2009, 48, 6394-6396.

6.    H.B. Bode and Rolf Müller*, Secondary metabolism in Myxobacteria (Chapter 15) in: Whitworth, D. (Ed) Myxobacteria: multicellularity and differentiation. ASM press, Chicago, 2007.

5.    H.B. Bode* and R. Müller*, Reversible sugar transfer by glycosyltransferases as a tool for natural product (bio)synthesis, Angew. Chem. Int. Ed. 2007, 46, 2147-2150.

4.    H.B. Bode and R. Müller*, Analysis of myxobacterial secondary metabolism goes molecular, J. Ind. Biotechnol. Microbiol. 2006, 33, 577-588.

3.    H.B. Bode and R. Müller*, The impact of bacterial genomics on natural product research, Angew. Chem. Int. Ed. 2005, 44, 6828-6846.

2.    H.B. Bode and R. Müller*, Possibility of bacterial recruitment of plant genes associated with the biosynthesis of secondary metabolites, Plant Physiol., 2003, 132, 1153-1161.

1.    H.B. Bode, R. Höfs, B. Bethe, A. Zeeck*, Big effects from small changes: possible ways to explore nature´s chemical diversity, ChemBioChem, 2002, 3, 619-627.

Weitere Publikationen (not peer-reviewed) - Further publications (not peer-reviewed)

8.    F.I. Nollmann, C. Dauth, D. Reimer, Q. Zhou, H.B. Bode*, Peptides in Xenorhabdus and Photorhabdus spp., Proceedings of the 32nd European Peptide Symposium (Ed. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas), 2012, 284-285.

7.    H.B. Bode*, Insektenpathogene Bakterien als Quelle neuer Naturstoffe in D. Jahn (Ed.) Zellbiologie und Mikrobiologie – Das Beste aus BIOspektrum, 2012, 51-55.

6.    H.B. Bode*, Drugs from bugs that kill bugs, Microbiology Today, 2012, 216-219.

5.    H.B. Bode*, Insektenpathogene Bakterien als Quelle neuer Naturstoffe, Biospektrum, 2010, 266-270.

4.    A.O. Brachmann, G. Schwär, H.B. Bode*, Photorhabdus and Xenorhabdus: potent secondary metabolite producers, Scientific program of the IOBC/WPRS 11th European meeting “Insect pathogens and entomoparasitic nematodes" in cooperation with COST Action 862 “Bacterial toxins for insect control", Bulletin IOLB SROP, 2008, 31, 151-156.

3.    H.B. Bode*, No need to be pure: mix the cultures!, Chem. Biol. 2006, 13, 1245-1246.

2.    H.B. Bode*, Mehr als nur Naturstoffe, transkript 2006, 12, 55 (Tagungsbericht über die 18. Irseer Naturstofftage (DECHEMA) vom  22.02.-24.02.2006).

1.    H.B. Bode*, „Junge“ Naturstoffchemie, Nachrichten aus der Chemie, Ntps://, 49, 951 (Tagungsbericht über die 13. Irseer Naturstofftage (DECHEMA) vom 28.02.-02.03.2001).


Prof. Dr. Helge B. Bode
Campus Riedberg
Gebäudeteil 250, Raum 0.04
Max-von-Laue-Str. 9
60438 Frankfurt am Main

T +49 6421 178-501
F +49 69 798-29527

Sophie Moktadir
Campus Riedberg
Gebäudeteil 250, Raum 0.04
Max-von-Laue-Str. 9
60438 Frankfurt am Main

T +49 69 798-29558
F +49 69 798-29527

08:00 Uhr bis 12:00 Uhr