As a model organism, we use the zebrafish embryo. This model offers many advantages for research since the embryos can be easily obtained in large numbers and their external development is rapid. Most important, they are fully transparent which enables the observation of the organ development at high resolution and in living organisms.
Main methods that we currently use in the lab:
Live imaging using spinning disc confocal microscopy
Generation of mutants using TALEN and Crispr/cas9 system
In situ hybridization and immunostaining
Quantitative image analysis
Prof. Dr. Virginie Lecaudey Biologicum | Campus Riedberg Building part B | Room 2.218 Max-von-Laue-Str. 13 60438 Frankfurt am Main