Evolutionary genomics of vertebrates

Prof. Dr. Axel Janke, ajanke@senckenberg.de, Tel. 069 7542 1842

Module information

Vertebrate Genomics

It was the ultimate dream of Mendel, Flemming, Darwin, Morgan, Boveri, Sutton, Avery Dobzhanski, Haldane, Chargaff, Watson and many other heroes on whose shoulders we stand, to be able to sequence, assemble and annotate the ultimate information about an organism. Everything that makes a tree, a toad, a tiger, or you is encoded in its genome.


Now imagine for a moment that you had the power to sequence a genome and unlock one of nature's deepest and best-kept secrets. But remember, with great power comes great responsibility.


Then you need to join our Vertebrate Genomics Master Module. In just seven weeks you will learn how to:

- isolate DNA suitable for genome sequencing

- prepare the DNA to be loaded onto a marvel of modern technology, a Next Generation Sequencer

- handle UNIX and scripting

- assemble and annotate a de novo genome from scratch, and then

- process and analyze more data than you could ever read in a thousand lifetimes.

Afraid of computers? Don't be. A crash course will teach you everything you need to know to turn that silly piece of plastic, silicon and metal into your own personal servant. It will do what you want it to do and not you reacting to audio-visual input. You will get your first taste of diving into the exciting world of the evolutionary mysteries of an organism, learning all about its present (genomic diversity), past (phylogeny) and future (gene defects). But be warned: once you've tasted the forbidden fruit, there's no turning back.

Still not enough? Then join the team of comrades and write a scientific publication about the new genome assembly, a peer-reviewed publication with your name on it. Yes, you heard right, if you are a team-player, you will get the chance to have your first scientific publication.

Don't miss out on this career boost.

Time slot of the module – second half of the winter semester

Number of participants - 10

Homepage of the working group

AK Janke